Dermatitis skinrash lupus nephrology treatment erythematosus medications drugs reactions systemic hypersensitivity differential dermatology

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Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
- Inflammatory

• Bullous systemic ... lupus erythematous ... • Phototoxic drug ... Vesiculobullous #SkinRash ... #dermatology #Differential

Hypersensitivity: Summary
Type I Hypersensitivity:
• Immunological Mediator: lgE
• Immunological Target: Allergen Molecules
• Ex: Antibiotic

Penicillin-induced drug ... complexes • Ex: Systemic ... Lupus Erythematosus ... Syndrome, Contact Dermatitis ... (ie. reaction to

Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents

Drug Reaction with ... Eosinophilia and Systemic ... hypersensitivity ... to medication ( ... #SkinRash #DRESS

Summary table of types of hypersensitivity reactions.
Type 1
- Mediators: lgE
- Antigen Form: Soluble

table of types of hypersensitivity ... Food allergies, Drug ... glomerulonephritis, Systemic ... lupus erythematosus ... Examples: Contact dermatitis

Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
- Allergen-specific lgE antibodies bind

Hypersensitivity ... allergies, and drug ... lupus erythematosus ... - Contact dermatitis ... Allergy #Diagnosis #Reactions

Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
• Scarring Alopecia:

Allopecia - Differential ... erythematosus, ... erythematosus, ... Vitamin D levels Systemic ... #Diagnosis #dermatology

Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
•

Drug Induced Systemic ... Lupus Erythematosus ... for 1 year of treatment ... #Lupus #Erythematosus ... #medications #drugs

Causes of Acute Pericarditis:

Infectious;

Viral:
Adenovirus
Coxsackie virus A and B
Echovirus
Epstein-Barr virus
Hepatitis
Human immunodeficiency

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