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diagnosis differential cardiology secondary chronic generalized hematology pruritus common cvid dyspnea fatigue hemeonc hemophagocytic hlh hypogammaglobulinemia immunodeficiency immunology infectiousdiseases lymphohistiocytosis
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Iron deficiency anemia ... • Bacterial endocarditis ... • Nephrotic syndrome ... #Secondary #dermatology ... #causes
Systolic Murmurs - Differential Diagnosis Algorithm Benign / Flow / Hyperdynamic: • Pregnancy • Fever • Anemia Supravalvular
Systolic Murmurs ... Differential Diagnosis Algorithm ... • Fever • Anemia ... Heart Disease Pulmonary ... #causes
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm Pericardial • Effusion • Cardiac Tamponade* • Constriction Myocardial •
Differential Diagnosis Algorithm ... Myocardial • Systolic ... Acute Coronary Syndrome ... - Other • Anemia ... #Causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Primary Causes ... renal failure/uremia ... Myelodisplastic syndrome ... #generalized #dermatology ... #causes
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Hematologic • Anemia ... Infectious • Endocarditis ... Chronic Obstructive Pulmonary ... Chronic Fatigue Syndrome
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Vascular: • Systemic ... Cerebral > Splenic, pulmonary ... Septic Emboli Cause ... Leukocytosis, anemia ... #diagnosis #management
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
iron deficiency anemia ... disorders - Chronic pulmonary ... Acute Coronary Syndrome ... • Infective Endocarditis ... Infarction • Pulmonary
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #secondary #systemic ... #generalized #dermatology ... #causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... ) • Systemic granulomatous ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Vascular: • Systemic ... Cerebral > Splenic, Pulmonary ... Cholesterol emboli syndrome ... Septic emboli cause ... Leukocytosis, anemia
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