11 results
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Rashes- THE ALGORITHMIC ... ; however, an algorithmic ... While all patients ... #Diagnosis #Dermatology ... Purpuric #Rash #Algorithm
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... ITP • SLE • CLL ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Significant ↓ PLT: Petechiae ... - infiltrates (anemia ... , thrombocytopenia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... cells - Sickle cell ... PD deficiency, Pulmonary ... Thrombotic idiopathic thrombocytopenia ... #differential #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
History of bleeding (petechiae ... changes), high MCV anemia ... not required in all ... or if a primary hematologic ... Causes #Workup #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... • Neutropenia, anemia ... , thrombocytopenia ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... 5) Symptoms of anemia ... or thrombocytopenia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Consider sickle cell ... Schistocytes, thrombocytopenia ... #workup #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... infections/fevers • Thrombocytopenia ... bleeding, and petechiae ... #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... caused by bleeding (petechiae ... IDUS) • Immune Thrombocytopenia ... Syndromes #diagnosis #hematology ... #oncology