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diagnosis differential hemolytic management algorithm causes leukemia monoclonal chronic hemolysis lymphocytic mds mgus myelodysplastic syndrome apml arterial bandemia cbc cell
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Increased red cell ... Increased red cell ... Hemolysis #Hemolytic #Anemia ... Differential #Causes #Workup ... #Hematology #Diagnosis
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... Microangiopathic hemolytic anemia ... non-specific red cell ... intravascular coagulation ... #Hematology #Pathology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
incompetent • CLL ... • Neutropenia, anemia ... leukemia #CLL ... Leukemia #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... - infiltrates (anemia ... ) CLL Symptoms: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Microangiopathic hemolytic anemia ... intravascular coagulation ... ) (e.g. lupus, CLL ... differential #diagnosis #hematology ... #anemia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... Allogeneic stem cell ... Management #treatment #hematology ... #oncology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Mean corpuscular (cell ... Red cell distribution ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
40 ml/min A - Anemia ... marrow plasma cell ... diseases, CML, ... MGUS #diagnosis #hematology ... #oncology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... ARUPLabs #Hemolytic #Anemia ... Diagnosis #Algorithm #workup ... #hematology #testing
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... 5) Symptoms of anemia ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
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