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Hemolytic Anemia - Hemolysis Diagnostic Workup

Infographic by: Howard Ong

#Hemolysis #Hemolytic #Anemia #Algorithm #MAHA #TTP #Diagnosis #Workup
Hemolytic Anemia ... Workup Infographic ... #Hemolytic #Anemia ... Algorithm #MAHA #TTP ... #Hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... Differential Diagnosis Table ... #Anemia #AIHA # ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia ... Diagnosis #Algorithm #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... thrombocytopenia - DIC, TTP ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... anemia Indirect ... impairment #TTP ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
PCH • Evans • ITP ... • Coombs (-) hemolytic ... anemia due to cold ... beds-renal, retinal, DVT ... Paraproteinemias #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... cell aplasia • ITP ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Thrombocytopenia (ITP ... factor (GCSF) treatments ... Workup: • Complete ... Syndromes #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... anemia • Pain ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology