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diagnosis hematology pediatrics differential abcde abcs algorithm alopecia bleeding chronic cll color cpap ddxof disorders genetics hair hairloss history leukemia
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
red-flags to exclude dermatologic ... Ill-appearing, vital sign ... sulfa-drug - Skin ... #Diagnosis #Dermatology ... Maculopapular #Scaling
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms ... stature • Poor suckling ... #genetics #pathophysiology ... #peds #pediatrics
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Capitis - Skin ... , Loose anagen syndrome ... Examination: • Signs ... Examine the entire skin ... Differential #Diagnosis #dermatology
Management of Serotonin Syndrome Identify and stop all serotoninergic medications • Avoid inadvertent Rx of serotoninergic meds
Management of Serotonin ... Syndrome Identify ... serotoninergic meds ... normalize vital signs ... symptoms continue UCSD
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... TLS #diagnosis #management ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Hepatomegaly • Skin ... • Matute’s CLL Scoring ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... nodes: 13-15%, skin ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
membrane bleeding and skin ... haemophilia • Scarring ... Marfan syndrome, ... Disorders #History #peds ... pediatrics #diagnosis #hematology
Continuous Positive Airway Pressure in the Neonate WHY CPAP? • Maintain airway patency • Helps avoid alveoli
baby ABCDE - CARING ... auscultate for signs ... break down of skin ... CPAP #Neonate #Management ... #ABCs #ABCDE #Peds
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