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oncology management algorithm anemia differential hepatology hodgkins lymphoma rheumatology agglutinin aplastic cancer chronic cll cold comparison congenital cryofibrinogenemia differentiation disease
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
of about 30% of normal ... as jaundice on clinical ... examination; nonspecific symptoms ... #hepatology #diagnosis ... #gastroenterology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... #APML #diagnosis ... #management #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
translocation • Types ... : Classification ... on: - Cell type ... also arise in normal ... #differential #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... transformation to AML ... low and appear abnormal ... progression to AML ... #diagnosis #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
symptoms/signs ... presence of metabolic syndrome ... Areas of diagnostic ... disease; T2DM, type ... #Algorithm #Hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Disease 3 Types ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... hemolytic #anemia #hematology ... #diagnosis
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... Divided Into Two Types ... : • + Clinical ... Antiphospholipid syndrome ... hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... workup #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... (MDS) (normal or ... • Improve the symptoms ... Anemia #oncology #hematology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Skin Disease Classification ... Kikuchi disease • Type-I ... Clinical Features ... Induced Lupus: • Symptoms
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