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agglutinin apml cold disease erythematosus hemolytic lupus management mds mgus monoclonal myelodysplasia myelodysplastic rheumatology significance sle syndromes systemic undetermined
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... No evidence of anemia ... constitutional symptoms ... level (non-IgM type ... #diagnosis #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation ... Syndrome in APML ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... #hematology #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Disease 3 Types ... Cold Agglutinin Syndrome ... anemia • Cold ... IgM monoclonal gammopathy ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... One blood cell type ... of one or more types ... #diagnosis #hematology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Differential Diagnosis ... Kikuchi disease • Type-I ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms
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