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Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Systemic Lupus Erythematosus ... Systemic #Lupus #Erythematosus ... nephrology #nephritis #classification ... #types #rheumatology
Lupus Nephritis Classification Algorithm

#Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis Classification ... Lupus #Nephritis #Classification ... #Algorithm #diagnosis ... #differential #types ... #rheumatology #
Cryoglobulinemia Classification Types

Type 1: Monoclonal IgM (rarely IgG/lgA)
 • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Cryoglobulinemia Classification ... Types Type 1 ... Cryoglobulinemia #Classification ... #Types #hematology ... #diagnosis
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
antiphospholipid syndrome ... 1 (50%-80%), type ... Systemic Lupus Erythematosus ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Classification of ... systemic lupus erythematosus ... Vasculitis #Vessels #Diagnosis ... #Rheumatology # ... Diagnosis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Vesicopustule on erythematous ... Antiphospholipid-antibody syndrome ... Discoid lupus erythematosus ... #differential #diagnosis ... #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... systemic lupus erythematosus ... Cryoglobulins #diagnosis ... #types #classification ... #rheumatology #
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
systemic lupus erythematosus ... #Classification ... #Pathophysiology ... #Allergy #Diagnosis ... #Reactions #Table
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Systemic lupus erythematosus ... Systemic lupus erythematosus ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Cutaneous Lupus Erythematosus
 • Acute Cutaneous Lupus (ACLE)
 • Neutrophilic Dermatoses 
 • Vascular Lesions
 •
Cutaneous Lupus Erythematosus ... Cutaneous #Lupus #Erythematosus ... #diagnosis #types ... #venn #rheumatology ... #classification