33 results
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... Primary Biliary Cirrhosis ... onset Anti-U3RNP (fibrillarin ... Autoantibodies #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... /DM), Systemic sclerosis ... Primary Biliary Cirrhosis ... ANA #patterns #rheumatology ... #diagnosis #differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... 65 years PBC Pathophysiology ... PBC Signs and Symptoms ... cholestasis, Primary sclerosis ... #workup #hepatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... • Multiple sclerosis ... BEE #Syndromes #neurology ... #differential #diagnosis
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
- Differential Diagnosis ... • Meniere's Disease ... symptoms/signs, ... • Multiple sclerosis ... Dizziness #Vertigo #Neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... Diagnosis - Based ... objective evidence of neurologic ... #diagnosis #management ... #neurology #treatment
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
C’s of Primary Sclerosing ... asymptomatic at diagnosis ... Care focuses on symptom ... management. ... #Hepatology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
and Pathophysiology ... regurgitation - Aortic sclerosis ... - Obesity - Cirrhosis ... coronary heart disease ... #Pathophysiology
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
Méniére's disease ... Multiple sclerosis ... Disease onset usually ... #differential #diagnosis ... #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... #management #treatment