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hematology differential leukemia treatment chronic liver lymphocytic neurology rheumatology abnormal aflp apml barre cancer causes classification common cvid differentiation encephalopathy
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... extramedullary disease ... ) CLL Symptoms: ... Transformation: • Complication ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Diagnosis: • ... cells can indicate disease ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... thrombocytopenia Complications ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Heavy Chain disease ... Sneddon-Wilkinson disease ... #Differential #Diagnosis ... #Oncology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... ↓Antithrombin Ill ... Monitor and Treat Complications ... Liver #Pregnancy #hepatology ... #management #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... #management #hematology ... #oncology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... , signs, and complications ... • Treatment algorithms ... von Willebrand disease ... #treatment #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... noninfectious complications ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... age 70 years Symptoms ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... suspicious clinical symptoms ... box indicates all ... presence of metabolic syndrome ... #Hepatology #Liver
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