10 results
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology ... tissue damage - CXR ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... production of pro-inflammatory ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... Leishmaniasis Differential ... #Syndrome #Differential ... #Diagnosis #Management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Summary Lung ... polymicrobial infection ... Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... causes #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... , Hep A/B/CMV, TB ... #management #neurology ... #differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Sclerosis (ALS) Summary ... cells are the immune ... can become pro-inflammatory ... - Causes progressive ... #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Summary Epidemiology ... activity → local immune ... renal failure Clinical ... e.g. incidental CXR ... #Management #Signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... affects the skin, neurologic ... tract, and often causes ... syndrome: Ocular inflammatory ... #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... Erythema nodosum • Immune ... Immunohistochemical studies (to differentiate ... #oncology #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
common systemic inflammatory ... with systemic, neurologic ... Diagnosis = clinical ... vs infection vs ... #Management