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apml gap globulin management mds myelodysplasia protein proteingap secondary syndromes thrombocytosis
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
thrombocythemia (ET) • Polycythemia ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... #Diagnosis #Causes ... #hematology #secondary
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... #Syndromes #diagnosis ... #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation ... Syndrome in APML ... Imaging: CXR- pulmonary ... initiation • Differential ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... Liver disease: Cirrhosis ... gastric tumors • Hematology ... #diagnosis #hematology
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