8 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Lupus Cerebritis ... #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
(HLH) Pathophysiology ... →Activation of CD8 ... Autoimmune diseases: SLE ... #diagnosis #management ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... HLH signs and symptoms ... #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus [SLE ... ], AOSD) • Infection ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... complex → plt activation ... Confirmatory test ↑Se ... #Management #Treatment ... #Hematology #HemeOnc
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Excessive activation ... Transverse Myelitis - Clinical ... Bilateral signs and/or symptoms ... #management #neurology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Rheumatologic ... has five major clinical ... Aspergillosis Pathophysiology ... ) #Mycoses #InfectiousDiseases ... #Management #Infections
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including systemic lupus ... erythematosus (SLE ... and the systemic symptoms ... Hypoalbuminemia Treatment ... #management #rheumatology