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differential signs hematology treatment syndrome classification infections infectiousdiseases ra vasculitis aids amiodarone anemia aplastic apml arteritis arthritis autoimmune boop cardiology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
: ILD (interstitial ... lung disease), ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
Unknown • 6-7 cases ... Organizing Pneumonia - Diagnosis ... Pneumonia #COP #BOOP #pulmonary ... #ILD #diagnosis ... #management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced Lung ... Direct cytotoxic lung ... gradually with symptoms ... Improvement in symptoms ... #diagnosis #management
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
inflammation tends to cause ... interstitial lung ... disease/pulmonary ... pathophysiology #signs #symptoms ... #diagnosis #ExtraArticular
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
- Differential Diagnosis ... blood cells in the lung ... 10,000 ft) • Symptoms ... interstitium and ... #differential #diagnosis
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
higher incidence in lung ... extralymphatic tissues Diagnosis ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... granulomas within the lungs ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary ... #Management #Signs
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
or serologies + symptoms ... Goodpasture's cause ... sparing of the lung ... hematuria, RBC casts ... #management #treatment
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung ... Granulomatous lymphocytic interstitial ... lung disease (GLILD ... DDX - Other causes ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... opacities • Diagnosis ... : >3 symptoms, or ... #management #hematology ... #oncology
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