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management aids barre hiv causes dementia disorder encephalopathy guillainbarre myasthenia myelitis neurocognitive opportunistic posterior pres reversible rhabdomyolysis transverse weakness
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Associated with: ... life-threatening Differential ... PCB variants of GBS ... precipitated by: Drugs, infection ... #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... response preceding infection ... GQ1b IgG Antibody associated ... #treatment #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
pulmonary etc) • CNS ... Postsynaptic: Myasthenia Gravis ... Lack of UMN/LMN signs ... Neoplastic: Malignancy-associated ... #Diagnosis #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... cauda equina TREATMENT ... #Syndrome #diagnosis ... #management #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in ... should be based on clinical ... Antimicrobial treatment ... #Infections #differential ... #Neurology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... infects the CNS ... Diagnosis: MRI ... syndrome of HAD ... dementia #AIDS #Neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... fluctuations PRES-Associated ... Etiology: • Pathophysiology ... Reversible course Differential ... #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Diagnosis Framework ... Statins - ETOH - Infection ... Dermatomyositis Clinical ... Heme associated ... #nephrology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... • Bilateral signs ... #management #neurology ... #differential
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