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diagnosis management hematology hemophagocytic lymphohistiocytosis nephrology oncology syndrome activation antinxp2 behcet causes classification dermatology dermatomyositis differential diuresis diuretics excretion hodgkins
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... Ferritin >500 ng/mL ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
common in Asia • HLA-B51 ... aseptic meningitis), MCC ... : Arterial (MCC-small ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's lymphoma (HL ... (MCHL) - Lymphocyte ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
intracranial pressure • Dialysis ... Inhibitors of Na+K+2Cl ... chronic kidney disease ... Tolvaptan) • Treatment ... #Medications #Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Treatment of underlying ... disease 2. ... urine output: 200 ml ... per day until stable ... Dialysis for severe
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
dorsal part of the MCP ... had more severe disease ... positive patients Treatment ... three days #AntiNXP2DM ... diagnosis #management #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelogenous Leukemia (CML ... Myeloproliferative Disease ... factor (GCSF) treatments ... appear normal, but analysis ... Syndromes #diagnosis #hematology
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