8 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
blood vessels leading ... Crises can be precipitated ... The underlying pathophysiology ... of capillaries leading ... 2) Aplasia - Acute
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Hydroxychloroquine - Risks ... other medications leading ... rare with ~100 cases ... - Cuteanous: acute ... #sideeffects #rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Low Grade - Slow growing ... Treated Like Acute ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Manifestations Causes ... rice/processed grains ... Findings: • Acute ... syndromes #beriberi #nutrition ... #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
• Hypertensive crisis ... Etiology: • Pathophysiology ... syndrome, ADEM, Acute ... the underlying cause ... - Lower the diastolic
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... on bone marrow leading ... ALL (Acute Lymphoblastic ... -> AML: Blast crises ... #Leukemia #Hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... monophasic Pathophysiology ... than 2/3 of the cross-sectional ... • Infectious causes ... antibodies • Nutritional
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Scleroderma Renal Crisis ... : 1) Acute kidney ... anemia (MAHA) Pathophysiology ... • Refractory cases ... #rheumatology #