13 results
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
: Most Common Causes ... Androgens: • Symptoms ... physical: - Symptoms ... addisons #disease #endocrinology ... diagnosis #signs #symptoms
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Rickets Dysmorphic Features ... • Congenital Adrenal ... Celiac, IBD) • Renal ... Diagnosis #Algorithm #endocrinology ... #causes #pediatrics
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
: Most Common Cause ... Adrenalitis Other causes ... ketoconazole, etomidate) Symptoms ... Causes of Secondary ... Diagnosis #Management #Endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Acne • Coarse features ... diagnosis #signs #symptoms ... #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... 21-OHD in the adrenal ... as "congenital adrenal ... Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
, oral cavity) Caused ... , pathological fractures ... the abdomen for adrenal ... Diagnosis #signs #symptoms ... #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... patient has good renal ... Signs/Symptoms/Complications ... Abdominal pain, nausea ... pathophysiology #endocrinology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
, and possibly renal ... failure Clinical Features ... : • Many symptoms ... patients have no symptoms ... Management #Signs #Symptoms
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • recurrent fractures ... mineralization Symptoms ... pain - Frequent fractures ... Phosphatase: • Other causes
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
patient has severe symptoms ... • Discuss with endocrinology ... — discuss with endocrinology ... SIADH — look for cause ... hourly • Identify Cause