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diagnosis management treatment rheumatology idsa opportunistic prevention differential infectiousdiseases latenttb tb tuberculosis algorithm comparison disease hematology lupus testing active adverseeffects
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
to decrease the risk ... • The lifetime risk ... infection in patients ... or intermediate risk ... used to exclude pulmonary
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
lymph nodes Risk ... • Pulmonary fibrotic ... • HIV: 2/3 pulmonary ... destruction (including pulmonary ... Inhibitor: • Risk
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
lymph nodes Risk ... • Pulmonary fibrotic ... • HIV: 2/3 pulmonary ... destruction (including pulmonary ... Inhibitor: • Risk
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm Congenital Anomaly / Disorder: •
Neurologic Anomaly • Pulmonary ... Metabolic Disorders Infection ... Gastrointestinal infection ... Sudden Infant Death Syndrome ... 80% of SUDI • Risk
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Benefits: ↓ Disease activity ... Thrombosis, ↓ Severe infection ... Cardiovascular risk ... deficiency [(limited) risk ... Benefits #Lupus #pharmacology
IDSA Recommendations for Preventing and Treating Chagas Disease (American Trypanosomiasis) in HIV-AIDS Preventing Clinical Disease Indication: Individuals
with epidemic risk ... patients are still at risk ... opportunistic #infections ... #HIVAIDS #pharmacology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Food products Risk ... Illnesses: • Pulmonary ... Lady Windermere Syndrome ... : • Syndrome of ... complicate MAC pulmonary
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Attempt if high risk ... Imaging: CXR- pulmonary ... Differential Diagnosis: Infection ... Differentiation #Syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
effusion, INC risk ... PE, Pulmonary amyloidosis ... Malignancy Risk ... lubricants • Pharmacologic ... muscarinic agonists • Active
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... extremity edema, active ... correlates disease activity ... CRP normal, ESR active ... Thrombosis highest risk
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