16 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... seizure, primitive reflexes ... #diagnosis #signs ... #symptoms
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
such as reflex ... carotid sinus syndrome ... further guide management ... orthostatic vital sign ... Further diagnostics
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... of normal leg reflexes ... pathophysiology #diagnosis ... #symptoms #signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
and Management ... extrapulmonary cases ... Clinical Signs ... years - May have signs ... numbness, decreased reflexes
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... at the time of diagnosis ... #Sarcoidosis #Diagnosis ... #Management #Signs
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Hyperreflexia, Clonus, Babinski ... Multiple Sclerosis Diagnosis ... Signs and symptoms ... #management #neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Decreased / Absent Reflexes ... Guillain-Barre Diagnosis ... Albuminocytologic dissociation ... #diagnosis #management
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
bilateral, malignant, pediatric ... cases, not associated ... and Signs: 50% ... and signs: • ... hypotension (may reflect
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... and signs below ... Non-compressive Spinal Cord Causes ... MCTD, Sjogren syndrome ... dysfunction • Abnormal reflexes