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hematology syndrome anesthesiology checklist workup intraoperative dermatology hemophagocytic lymphohistiocytosis lupus sle blood cardiology clinical differential erythematosus hyperthermia medications neurology pharmacology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Treatment: • ... #management #treatment ... #summary #rheumatology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... #Differential #Causes ... #Checklist #Diagnosis ... #Management #Workup
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... Diagnosis via genetic ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia • Unexplained hypotension • Unexplained bronchospasm (wheeze may be absent
trolley, anaphylaxis treatment ... as a possible cause ... require prolonged treatment ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
thoracotomy is a better treatment ... Plan definitive management ... improvement By Association ... Anesthesiology #Anesthesia ... #Management #Workup
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... or autoimmune disease ... for refractory disease ... #Treatment #management ... #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... normal in mild cases ... Avoid meds that ... #Management #treatment ... #hematology
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia Unexplained increase in ETCO2 AND tachycardia AND increased
other, more common causes ... ❹ Call for MH treatment ... Anesthesiology #Anesthesia ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
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