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classification vasculitis ana antinuclear disorders erythematosus glomerulonephritis hematology lupus lymphomas lymphoproliferative management nonhodgkin pathophysiology patterns progressive rapidly rpgn sjogrens sle
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Purpura Anti-GBM antibodies ... With associated pulmonary ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... Amy Chung, MD, MSc ... #Diagnosis #NonHodgkin ... #differential # ... algorithm
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Using fluorescence ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... Diagnosis Framework ... disease, and ocular ... C-ANCA) pattern: antibodies ... #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... phenomenon (16%) MSK ... Sjogrens #Syndrome #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Non-autoimmune rheumatologic ... #Rheumatology
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