12 results
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
Testing LATENT TB ... intermediate risk of disease ... immunocompromised (e.g., AIDS ... used to exclude pulmonary ... LatentTB #ActiveTB #InfectiousDiseases
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Chronic kidney disease ... • HIV: 2/3 pulmonary ... Tuberculosis Diagnosis ... Tuberculin skin test ... #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Chronic kidney disease ... • HIV: 2/3 pulmonary ... Tuberculosis Diagnosis ... Tuberculin skin test ... #Diagnosis #Management
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
failure • Severe pulmonary ... disease ARDS Diagnosis ... agglutination - test ... #microbiology #diagnosis ... #treatment #management
Sporotrichosis - Sporothrix schenckii - Diagnosis and Management Summary
Sources: 
 • Landscaping, Christmas tree farming, Rose
and Management ... • Pulmonary Sporotrichosis ... Lymphoma or AIDS ... CSF similar to TB ... #infectiousdiseases
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
and Management ... , Advanced HIV/AIDS ... presentations: • Pulmonary ... vori Infectious Diseases ... #fungal #infectiousdiseases
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
treatment of HIV/AIDS ... worsening of that disease ... be present: • AIDS ... pericarditis, peritoneal disease ... #Management
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
Infection and Disease ... in HIV-AIDS Treating ... (+) screening test ... and molecular diagnostic ... Prevention #Treatment #management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
extrapulmonary disease ... or meningitic disease ... yeast • At risk: AIDS ... ) #Mycoses #InfectiousDiseases ... #Management #Infections
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Framework Disease ... infiltrates, mimicking TB ... Infections #HIV #AIDS ... #pulmonary #differential ... #diagnosis #infectiousdiseases