20 results
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Conditioning regimen Signs ... , unexplained hematologic ... EBV viral load, signs ... and classification ... to 50% of PTLD cases
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Management Summary Pathophysiology ... dermis Clinical Signs ... /Symptoms/Exam findings ... - Erosions and crusts
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Generalized Seizures and Pseudoseizures
Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
general seizure caused ... and metabolic causes ... Pseudoseizures #GrandMal #Classification ... #Diagnosis #Neurology ... #Signs #Symptoms
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Chondrodysplasia Neurologic ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... #workup #hepatology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
neuropsychiatric symptoms ... • Caused by liver ... of neurologic/cognitive ... Encephalopathy #Grading #Classification ... #treatment #hepatology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... fasciculations Common Symptoms ... Escorial criteria uses ... Lateral #Sclerosis #neurology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
anti-coagulation • Hematologic ... retinal edema caused ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic ... Phosphatase: • Other causes