9 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Syndrome Signs ... /Symptoms/Complications ... Incr Skeletal fractures ... • Obesity -> Type
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
Conditioning regimen Signs ... EBV viral load, signs ... and classification ... to 50% of PTLD cases ... Disorders #oncology #diagnosis
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
related to complications ... Sores, scars, calluses ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Hypercortisolism - Diagnosis ... , pathological fractures ... dehydrogenase type ... Hypercortisolism #Diagnosis ... #signs #symptoms
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
and Signs: 50% ... and panic attack-type ... and signs: • ... leukocytosis, psychiatric ... glucose, apparent type
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
increased risk of fracture ... mortality rates of all psychiatric ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... -> Pathologic fractures ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
Bulimia Nervosa: Complications ... hormone levels cause ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
ingestion and most cases ... make a clinical diagnosis ... Pathophysiology #Psychiatry ... #Diagnosis #Signs ... #Symptoms