10 results
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic Alkalosis ... - Differential Diagnosis ... Bartter Syndrome, Gitelman ... #Differential #Diagnosis ... #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... - Differential Diagnosis ... Bartter Syndrome, Gitelman ... #Differential #Diagnosis ... #Algorithm #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... nephron → - ↑ K+ ... Hypokalemia Metabolic alkalosis ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Hypomagnesemia - Metabolic Alkalosis ... Inappropriate renal K+ ... Fractional excretion of Cl ... #Workup #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Urine Cl - Non-reabsorbable ... • High Urine Cl ... Bartter syndrome, Gitelman ... differential #algorithm #diagnosis ... #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
- Metabolic Alkalosis ... Bartter syndrome, Gitelman ... #Hypokalemia #diagnosis ... differential #potassium #nephrology ... #low
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... • Normal/low ... Bartter syndrome, Gitelman ... urine #Algorithm #nephrology ... #differential #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... - Differential Diagnosis ... Bartter Syndrome, Gitelman ... #Differential #Diagnosis ... #Algorithm #Nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
• Normal or low ... Hypochloremic metabolic alkalosis ... #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Antibiotics (Bactrim, PCN ... reabsorption) Workup ... tourniquet / IVF line draw ... acidosis) • Low ... Treatment #potassium #nephrology