11 results
Arachidonic acid pathway and drugs which affect it.

#Pharmacology #Pathophysiology #ArachidonicAcid #Pathways #COX #Prostaglandins #Prostacyclins #Leukotrienes #Synthesis

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Arachidonic acid pathway ... and drugs which ... #Pharmacology #Pathophysiology ... ArachidonicAcid #Pathways ... #COX #Prostaglandins
Antiplatelet Drugs and their Actions

- Amy Chung, MD, MSc
@AmyChung

#Antiplatelet #Medications #Pharmacology #Pathophysiology #Drugs #Agents #COX #GIIbIIIa
Antiplatelet Drugs ... #Medications #Pharmacology ... #Pathophysiology ... #Drugs #Agents ... #COX #GIIbIIIa
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
Inflammation of Gout ... inflammation #gout ... #uricacid #pathophysiology ... #pharmacology # ... rheumatology
Fibrinolysis. 
Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
thrornbolytic drugs ... anticoagulant drugs ... #Fibrinolysis #Pathway ... #Pathophysiology ... #Plasminogen #Pharmacology
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
throughout body (mouth, gut ... Mesocortical Pathway ... Nigrostriatal Pathway ... irreversible • Drug ... #SideEffects #pharmacology
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The gout drug pegloticase ... #Homeostasis #Gout ... #Pathophysiology ... #Pharmacology #
Pathogenesis of Select Causes of Constipation in Adults and in Elderly

 • Mechanical (ex. Bowel Obstruction,
fibrosis of the gut ... unknown, many pathways ... colonic motility • Drugs ... excitatory neural pathways ... #constipation #pathophysiology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... disease states Pathophysiology ... activate inflammatory pathways ... Conditions for Gout ... #Comparison #rheumatology
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... Rapoport-Leubering pathway ... shifts the oxygen dissociation ... linked to some drugs ... the hemoglobin dissociation
Medications Contributing to Dysgeusia

Antimicrobial medicines	Macrolides, fluoroquinolones, ampicillin, metronidazole, tetracycline, trimethoprim-sulfamethoxazole, amphotericin B, terbinafine and other antimycotic
other antimycotic drugs ... procainamide HMG-CoA ... aripiprazole Gout ... Dysgeusia #Induced #Drugs ... Differential #Diagnosis #Pharmacology