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diagnosis anemia causes agglutinin cold enlarged extravascular hemolysis hodgkins intravascular lymphoma management oncology spleen splenomegaly testing
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
thrombocytopenic purpura ... ) (e.g. lupus, CLL ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... Consider sickle cell ... Consider RBC membrane disorder ... #workup #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Diagnosis Algorithm ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... Cell Disease (children ... #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... fatigue, pallor, dyspnea ... malignancies -> CLL ... younger pts) Differential ... #hematology #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Hodgkin Lymphoma - Clinical ... • Cough • Dyspnea ... Hodgkin Lymphoma Workup ... #hematology #oncology
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