41 results
The Cell Cycle
The cell cycle is the series of tightly regulated steps that controls cell growth
transcription factor E2F ... proliferation #TF #E2F
Determination of Volumes of Specific Body Fluid Compartments
#ExtracellularFluid #ECF #IntracellularFluid #InterstitialFluid #MedicalPhysiology #Physiology #TBW #ICF
ExtracellularFluid #ECF
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
The ECF and ICF ... of Cl- into the ECF ... remain in our ECF ... and enters the ECF ... much K+ in the ECF
92F w acute painless monocular vision loss. What's the diagnosis?

...

Central retinal artery occlusion (CRAO)! Retrobulbar "spot
92F w acute painless
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
mmol/L Raised ECF ... adequately Normal ECF ... cause Reduced ECF
Thiazide
diuretics
Carbonic anhydrase
inhibitors
(e.g., acetazolamide)
Nat-Cl symport
Na and HCO;-
reabsorption
Aldosterone
antagonists
(e.g., spironolactone)
Nat channel
(indirect effect)
Loop diuretics (e.g., furosemide)
Amiloride,
#triamterene
Nat-K+-2CF symport
Na channel
(direct effect)
#NaCI reabsorption
reabsorption + ECF
Non-alcoholic fatty liver disease algorithm.
 
For those patients with NAFLD or liver disease of unknown aetiology,
markers such as ELF ... force impulse; ELF
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Differential Diagnosis ECF ... villous adenomas ECF ... Liddle syndrome ECF
Dilated Cardiomyopathy - poor EF

Dr. J. Christian Fox @jchristianfox

#DCM #Dilated #Cardiomyopathy #Echocardiogram #POCUS #Clinical #cardiology
Cardiomyopathy - poor EF
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
prostaglandin E2 ... prostaglandin E2 ... prostaglandin E2