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Infection-Related Cancers
Viruses:
 • HPV - Cervical, anogenital, head and neck, skin cancer
 • HTLV-1 - Adult
Cancers Viruses: • HPV ... T-cell Leukemia • HIV ... cell carcinoma • HBV ... carcinoma • HHV ... Kaposi's sarcoma • EBV
Differential Diagnosis for Generalized Lymphadenopathy

Viral
• HIV 
• EBV 
• CMV 
• HBV 
• Dengue 
• Rubella
Lymphadenopathy Viral • HIV ... • EBV • CMV ... • HBV • Dengue
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
borrelia, Rubeola, HBV ... Coxsackie, CMV, EBV ... , HIV, HTLVI, Hantavirus
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Viral infections (HAV ... , HBV, HCV, HEV, ... EBV, CMV), Alcohol-related
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
• Infectious: HAV ... , HBV, HCV, HEV, ... EBV, HSV, CMV,
Hepatitis B Virus Serology and Interpretation
HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe
 - Acute
- Anti-HBe - ... replication - Inactive HBV ... carrier state (low HBV ... replication (high HBV ... #HepatitisB #HBV
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
• Infectious: HAV ... , HCV, HEV, EBV, ... HSV, CMV • Neoplasm
SCORTCH Congenital Infections Mnemonic
S - Syphilis
C - CMV
O - Other
R - Rubella
T - Toxoplasmosis
C - Chickenpox
Varicella) H - HSV ... , HIV, HTLV-1, HBV ... , HCV #SCORTCH
Autoimmune Hemolytic Anemia (AIHA)

WARM AHA
- Primary - Idiopathics
- Secondary
Infectious
 • Viral- HIV, EBV, HCV, HEV
 •
Infectious • Viral- HIV ... , EBV, HCV, HEV ... Infectious • EBV
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
detectable, high HBV ... undetectable, low HBV ... detectable, high HBV ... Indicated: • HBV ... Pregnancy with HBV