39 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium-Binding Agents ... KBinders #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Causes of Hypercalcemia - Differential Diagnosis Algorithm
 • Primary Hyperparathyroidism 
 • Possible Familial Hypocalciuric Hypercalcemia
Causes of Hypercalcemia ... Differential Diagnosis Algorithm ... Granulomatous Disorders (eg ... Differential #Diagnosis #Algorithm ... #Causes #endocrinology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding Agents ... constipation, diarrhea, nausea ... ); nausea, vomiting ... #pharmacology #table ... #comparison #binders
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... mmol/L - Consider cause ... clinical scenario, ECG ... Prevention - Consider cause ... #management #algorithm
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... repolarization causes ... in conduction causes ... #EKG #ECG #Changes ... #Progression #Table
Constipation - Differential Diagnosis Algorithm
Diet/Lifestyle
 • Fibre
 • Calories
 • Fluid
 • Exercise
 • Psychosocial
Medications
 •
Differential Diagnosis Algorithm ... Hypothyroidism • Hypokalemia ... • Hypercalcemia ... Differential #Diagnosis #Algorithm ... #Causes
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
- Medications (e.g ... cisplatin) - Chronic hypercalcemia ... - Chronic hypokalemia ... Differential #Diagnosis #Table ... #Causes
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Hyporeflexia: • Hypercalcemia ... Deep coma (any cause ... polyneuropathy (e.g ... differential #diagnosis #table
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... ECG changes, weakness ... injury, etc) ECG ... removal of offending agent
Treatment of Stable Narrow-Complex Tachycardia
Regular Rhythm:
 • Attempt vagal maneuvers
 • Give adenosine 6 milligrams IV
Treatment of Stable ... nodal blocking agents ... Treat underlying cause ... Treat underlying cause ... management #cardiology #algorithm