49 results
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... Summary Mechanisms ... cells, triggering insulin ... #Summary #DM2 # ... diabetes #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Summary Mechanisms ... • Increases insulin-mediated ... agent • Does not cause ... diabetes #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Summary Mechanisms ... glucose-dependent insulin ... side effects (e.g ... not definitively cause ... diabetes #endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Medication Guide Classes ... daily dose of insulin ... • Weight-based insulin ... #Medications #pharmacology ... comparison #table #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... and feet Excess Insulin ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Hypoglycemia - Differential Diagnosis Algorithm
Fasting Hypoglycemia:
 • Excess Insulin
 • Medications (e.g. Insulin Secretagogues, ß-Adrenergic Antagonists,
Hypoglycemia: • Excess Insulin ... Insulin Secretagogues ... Idiopathic Other Causes ... Diagnosis #Algorithm #endocrinology ... #causes
FIASP - Insulin Aspart vs Novolog

Have you heard about Fiasp, a new version of insulin aspart
FIASP - Insulin ... Fiasp is insulin ... control and can also cause ... #Pharmacology # ... EBM #Endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
along with IV insulin ... +++ fluids. 2) Insulin ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... Summary Vasopressors ... • Higher doses cause ... cAMP/cGMP • Causes ... #Summary #management
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
excess secretion of hCG ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology