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diagnosis management rheumatology peds treatment arms arteritis bleeding blood cerebritis classification cns cryofibrinogenemia cryoglobulinemia cryoglobulins disorders erythematosus gca giantcell history
Characteristic features of the rash are: -Rough texture (like sandpaper) -Worse in the skin folds e.g. groin, axilla,
-Worse in the skin ... folds e.g. groin ... Pastia’s lines) #Clinical ... #Dermatology #Peds ... #Pediatrics #SkinRash
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Rule out other causes ... antiinflammatory properties e.g ... Tetracyclines etc ... diagnosis #management #Dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... : • Clinical triad ... tissue disorder (e.g
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Clinical Manifestations ... unit activity on EMG ... of diazepam • EMG ... EMG Studies: ... Management #treatment #neurology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... required due to skip
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... Drug history, e.g ... connective tissue, e.g ... Marfan syndrome, ... #diagnosis #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... Causes purpura & ... infections with skin ... diagnosis #management #hematology
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