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diagnosis management rheumatology pediatrics treatment arms arteritis bleeding blood cerebritis classification cns crisis cryofibrinogenemia cryoglobulinemia cryoglobulins disorders encephalopathy erythematosus gca
Characteristic features of the rash are: -Rough texture (like sandpaper) -Worse in the skin folds e.g. groin, axilla,
-Worse in the skin ... folds e.g. groin ... Pastia’s lines) #Clinical ... #Dermatology #Peds
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Rule out other causes ... antiinflammatory properties e.g ... Tetracyclines etc ... diagnosis #management #Dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... : • Clinical triad ... tissue disorder (e.g
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Clinical Manifestations ... unit activity on EMG ... of diazepam • EMG ... EMG Studies: ... Management #treatment #neurology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... • EEG: With persistent ... the underlying cause ... Seizures: Treat with AEDs ... until cause identified
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... Serologic and EMG ... Clinical DX: - ... immunosuppressants - Meds ... diagnosis #management #neurology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... required due to skip
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... Drug history, e.g ... connective tissue, e.g ... Marfan syndrome, ... pediatrics #diagnosis #hematology
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