21 results
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Amyotrophic Lateral ... lateral sclerosis Pathophysiology ... - Causes progressive ... fasciculations Common Symptoms ... EMG: LMN Signs in
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... for secondary causes ... neoplasms) • Screen also ... organ-specific signs ... or symptoms (eg
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG
Problem Representation - Approach to the Infectious Disease Patient

Who: Patient age and host/risk factors (such as
factors (such as ... illness What: Key signs ... and symptoms that ... define the clinical ... illness script (e.g
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... Signs of immunodeficiency ... /Symptoms/Findings ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... renal failure Clinical ... mediators such as ... of diagnosis (e.g ... Diagnosis #Management #Signs
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... vision changes, etc
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... a clinical prognostic ... hypoxemia/Sepsis etc ... / hypoxemia -> focus
Paget’s Disease: Pathogenesis and Clinical Findings

 • Incr serum CTx - marker of bone resorption
 •
Pathogenesis and Clinical ... Skeletal-deformities- e.g ... PagetsDisease #pathophysiology ... #diagnosis #signs ... #symptoms
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Diagnosis and Clinical ... exposed tothe sun (e.g ... gluconeogenesis enzymes (e.g ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology