14 results
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Poliomyelitis, Guillain-Barre ... syndrome, Mononeuritis ... heavy metals), Critical ... , Myasthenia Gravis ... differential #diagnosis #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... Serologic and EMG ... Clinical DX: - ... Gravis #diagnosis #management ... #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... meningococcal, H1N1) Clinical ... Clinical Features ... #management #treatment ... #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Other brainstem syndromes ... (e.g. oculomotor ... , Myasthenia gravis ... Manifestations #diagnosis #neurology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Diagnosis: • Based on clinical ... serologic, and EMG ... - Improves clinical ... Gravis #diagnosis #management ... #neurology #treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... specific therapy, the clinician ... #Syndrome #diagnosis ... #management #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Cardiac, pulmonary etc ... • Acute stroke syndromes ... Postsynaptic: Myasthenia ... electromyographic (EMG ... Differential #Diagnosis #neurology
10 Steps to Managing Guillain-Barre Syndrome:
1️⃣ When to suspect
2️⃣ How to Diagnose
3️⃣ When to admit to
Managing Guillain-Barre ... Syndrome: 1️⃣ ... complications 8️⃣ Clinical ... GuillainBarre #Syndrome ... #Management #Neurology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Clinical Manifestations ... autoantibodies - TPO, TTG, etc ... SPS #Diagnosis #Management ... #treatment #neurology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... myopathy, Guillain-Barré ... Lambert-Eaton myasthenic ... (SAMS-CI) • EMG ... myopathy #diagnosis #management