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diagnosis hematology management clubbing differential syndrome ucsdh activation autoimmune comparison cryofibrinogenemia erythematosus gca giantcell hemeonc hemophagocytic hlh hodgkins lupus lymphohistiocytosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g ... Autoimmune diseases • Clinical ... Autoimmune diseases (e.g ... Malignancies (eg ... #differential #hematology
Clubbing of the Fiingers: Bulbous appearance of the distal fingers associated with a number of uncommon
lung conditions (e.g ... , IPF, cancer, etc ... Images #Clinical ... #Photo #Clubbing ... #Fingernails #UCSDH
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... vision changes, etc ... them, but urgent rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Fever is the main clinical ... underlying disease (eg ... • Infection (eg ... Diagnosis #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Still disease, dermatomyositis ... • Malignancy (e.g ... Endocrine disorders (e.g ... Induced Lupus: • Symptoms
Clubbing of the Fiingers: Bulbous appearance of the distal fingers associated with a number of uncommon
lung conditions (e.g ... IPF, cancer, etc ... Images #Clinical ... #Photo #Clubbing ... #Fingernails #SchamrothsSign
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... antiinflammatory properties e.g ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... Cryofibrinogenemia Symptoms ... Diagnosis: • + Clinical ... to medium-sized arteries ... #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... RP-ILD), dermato-rheumatologic ... symptoms • Anti-CADM ... • Nonerosive arthritis ... Myositis #Myopathy #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g ... Diagnosis #Management #Hematology
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