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diagnosis management hematology algorithm antinxp2 antinxp2dm arteritis blood differential disorders eosinophilia gangrenosum gca giantcell hemeonc hemophagocytic hlh lymphohistiocytosis oncology pg
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... , 500-1,500 cells ... (common causes ... signs or symptoms (eg ... Differential #diagnosis #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... Diagnosis = clinical ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... them, but urgent rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... antiinflammatory properties e.g ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... Muscle atrophy may cause ... Prednisone at 1 mg/kg ... diagnosis #management #rheumatology ... #dermatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... Causes purpura & ... potassium from lysed cells ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g ... Diagnosis #Management #Hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... plasmacytoma) Clinical ... red bone marrow, e.g ... Oncology #Diagnosis #Workup ... #Hematology
Pyoderma Gangrenosum (PG) 50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
wide variety of clinical ... neutrophils & T-cells ... medications in most cases ... corticosteroid (eg ... #photo #dermatology
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