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diagnosis hematology management neurology activation bleeding blood bloodbank cell differential disorders erythematosus history indications irradiated irradiation lupus macrophage mas oncology
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... Immunodeficiency Disorder, etc ... antithymocyte globulin, etc ... HLA-selected products (e.g ... #Indications #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... underlying disease (eg ... • Infection (eg ... Diagnosis #Management #Hematology ... #Rheumatology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Cardiac, pulmonary etc ... • Acute stroke syndromes ... dystrophies Work ... electromyographic (EMG ... Muscle Biopsy: Dermatomyositis
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Clinical Manifestations ... unit activity on EMG ... of diazepam • EMG ... antibody that works ... EMG Studies:
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... antiinflammatory properties e.g ... Tetracyclines etc ... #Rheumatology # ... diagnosis #management #Dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Still disease, dermatomyositis ... • Malignancy (e.g ... Endocrine disorders (e.g ... Clinical Features
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... Drug history, e.g ... connective tissue, e.g ... Marfan syndrome, ... pediatrics #diagnosis #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... red bone marrow, e.g ... Oncology #Diagnosis #Workup ... #Hematology
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