Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused T lymphocytes can engraft, proliferate & attack the host. - Congenital cellular immunodeficiency disorders (DiGeorge Syndrome, Severe Combined Immunodeficiency Disorder, etc.) - Intrauterine and neonatal transfusions up to four months of age - Patients with Hodgkin Lymphoma - Patients treated with immunosuppressive therapy (Alemtuzumab, antithymocyte globulin, etc.) - Hematopoietic stem cell transplant patients, both autologous and allogeneic - Individuals receiving HLA-selected products (e.g., HLA-matched, HLA-"compatible", or crossmatched platelets) - Individuals receiving blood donations from first- or second-degree relatives Daniela Hermelin, MD @HermelinDaniela #Irradiated #Irradiation #RBC #Blood #Transfusion #Indications #Hematology #BloodBank #Management
