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diagnosis rheumatology neurology differential erythematosus lupus signs systemic treatment acidosis arteritis barre blood cerebritis classification cns dermatology elevation encephalopathy gbs
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... unless worrisome EKG ... with tetany or cardiac ... TLS #diagnosis #management ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... cerebritis #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
(UPC) ratio • Cardiac ... recent DAN) • EMG ... or serologies + symptoms ... Goodpasture's cause ... #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... , and possibly renal ... failure Clinical ... of diagnosis (e.g ... neuropathy or cardiac
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... • Malignancy (e.g ... Endocrine disorders (e.g ... APLA/LAC: • Renal ... Induced Lupus: • Symptoms
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Clinical Presentation ... other pathology (e.g ... (short-acting, e.g ... • Refractory cases ... #Crisis #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... muscles: “myasthenic crises ... Serologic and EMG ... Myasthenia Crises ... Gravis #diagnosis #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... again we might see ... perfusion - Cardiac ... - Compartment syndrome
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
• Hypertensive crisis ... Immunosuppressive agents, Renal ... Neurological symptoms ... • EEG: With persistent ... #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Rule out other causes ... antiinflammatory properties e.g ... Tetracyclines etc ... diagnosis #management
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