19 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Fever is the main clinical ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
structural heart disease ... further guide management ... orthostatic vital sign ... should be guided by clinical ... The treatment strategy
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... age, however the disease ... Diagnosis: HLH signs ... #treatment #hematology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Diagnosis and Management ... Romana's sign ... Indeterminate form (No signs ... 20-90%, normal ECG ... , reactivation in
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... patients with clinically ... stimulation Clinical ... sclerosis #diagnosis #management ... #neurology #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... , dermatomyositis ... Non-autoimmune rheumatologic ... lymphoproliferative syndrome Clinical ... Chronic B-cell activation
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Herpes, Coxsackie, etc ... : Polymyositis/Dermatomyositis ... Clinical Features ... disease 2.
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #