14 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... of information (e.g ... non-essential drug/HDS treatments ... vascular disorder (e.g ... #Algorithm #hepatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
joint trauma (e.g ... subchondral bone (e.g ... derangements (e.g ... #approach #workup ... #differential #diagnosis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... syndrome - SLE Neurologic ... disease, Vasculitis (e.g ... #differential #diagnosis ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... glucocorticoid treatment ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Algorithm Endocrine ... Neoplastic / Hematologic ... • Rheumatoid Arthritis ... Pulmonary Disease Neurologic ... • Drug Abuse (e.g
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... claudication: pain ... Treatment of GCA
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... inflammatory disease (e.g ... Chemistry profile (e.g ... , and low back pain ... #laboratory #workup
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... thickening • Osteitis: pain ... and lower jaw Treatment ... antiinflammatory properties e.g ... Tetracyclines etc
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Fever is the main ... underlying disease (eg ... • Infection (eg ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis