5 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Drugs Oval Macrocytes ... Increased Requirement (e.g ... • Small Bowel Disorder ... #Causes #Hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (EPO), iron or B12 ... (BM) ablative disorders ... of substrate (e.g ... #Workup #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
(sometimes) Macrocytic ... RBC: Vitamin B12 ... Chemotherapy (e.g ... Unstable hemoglobin disorders ... Diseases #Red #BloodCell
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... dysfunction, and/or disorders ... : • Worsening macrocytic ... anemia, yellow ... Deficiency #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Prevalence: 1-2 cases ... and pernicious anemia ... antibody that works ... limb or joint disorders