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Proposed Algorithm for Diagnosing Sarcoidosis
Highly suggestive Clinicoradiological Findings → Clinical diagnosis (without biopsy) e.g. Löfgren's syndrome
Suggestive
without biopsy) e.g ... Löfgren's syndrome ... and/or cytology (e.g ... of alternative causes ... #Workup
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
- Cirrhosis Syndrome ... - Malignancy (e.g ... CNS pathology (e.g ... pathology (e.g. ... #Table #Causes
Chest Pain - Diagnosis and Workup Algorithm

History and Exam
Acute life-threatening causes:
 • Acute myocardial infarction
 •
Chest Pain - Diagnosis ... life-threatening causes ... Pneumothorax • Pulmonary ... : • EKG • Bedside ... #Chest #Pain #Diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... #Hematology
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
reactions, hematoma, pulmonary ... uptake and storage (eg ... miscellaneous causes ... (eg, spirochetal ... Classification #diagnosis
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
repolarization causes ... prolonged PR and QT ... #Diagnosis #Hyperkalemia ... #EKG #ECG #Changes ... #Progression #Table
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Hemoglobinopathies (e.g ... Membrane defects (e.g
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
polyneuropathy (e.g ... Guillain-Barré syndrome ... Hyperthyroidism, Serotonin syndrome ... #differential #diagnosis ... #table #neurology
Hypoxemic Respiratory Failure - Differential Diagnosis Framework
DECREASED INSPIRED OXYGEN
 • Low PATM Can decrease first part
- Differential Diagnosis ... High altitude (eg ... Intrapulmonary shunting (eg ... hepatopulmonary syndrome ... intracardiac shunting (eg
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm
Insufficient Sleep
 • Poor Sleep Hygiene
 • Insomnia
Sleep Deprivation (Eg ... Shift Work) Sleep ... Neurologic Disorders (Eg ... • Medications (Eg ... • Drug Abuse (Eg