21 results
Alice in Wonderland Syndrome
What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
Alice in Wonderland ... Syndrome What? ... (Many causes!) ... • Epilepsy • Psychiatric ... #diagnosis #neurology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
polyneuropathy (e.g ... injury, Early ALS ... Eclampsia, Late ALS ... #differential #diagnosis ... #table #neurology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
and Differential Diagnosis ... with previously stable ... hypertension and signs ... renal bruit or signs ... Neurologic disorders
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... unless worrisome EKG ... #TLS #diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... Escorial criteria uses ... EMG: LMN Signs in ... Lateral #Sclerosis #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... (for secondary APS ... Erythematosus #SLE #CNS #neurology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... mediators such as ... (e.g. incidental ... #Management #Signs
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
(SPS) - Diagnosis ... Prevalence: 1-2 cases ... Pathophysiology ... autoantibodies - TPO, TTG, etc ... Management #treatment #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Generalized fatigue - ALS ... Serologic and EMG ... test - Cogan sign ... - Peek sign ... #management #neurology