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differential coagulation prolonged treatment activation bleeding blood bruising dic disorders disseminated hemophilia hemostasis intravascular macrophage mas platelet product reactions rheumatology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... #PT #aPTT #Prolonged ... #Causes #diagnosis ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and the aPTT ... • Reduced liver ... #PT #aPTT #Prolonged ... #Causes #diagnosis ... #differential #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... : INR/PT, aPTT(liver ... gastric bypass), LFT ... #Causes #Workup ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... #Hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
mixing study (aPTT ... mild cases) • ... PT/INR & von Willebrand ... hemophilia type (e.g ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... DIC • Severe Liver ... #Coagulation #diagnosis ... #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... be performed PT ... , PTT, and fibrinogen ... #Workup #Hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... (e.g. incidental ... heart (2-5%), liver ... (pain/abnormal ... LFT): 12-20%, spleen
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
thrombocytopenia • Liver ... Hypofibrinogenemia • ↑ PT ... ↑ PTT • ↑ Fibrin ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
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