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differential coagulation aptt prolonged symptoms treatment arteritis ascites biliary blood cholangitis cirrhosis dic disorders disseminated gca giantcell hemophilia intravascular pbc
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... : INR/PT, aPTT(liver ... gastric bypass), LFT ... #Causes #Workup ... #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... amyloidosis #Abnormal ... #Causes #diagnosis ... #differential #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... #Causes #diagnosis ... #differential #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... failure PBC Signs ... or higher • Liver ... #workup #hepatology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... (e.g. cirrhosis ... Jcortesizaguirr #Ascites #workup ... #hepatology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... in mild cases) ... • PT/INR & von ... hemophilia type (e.g ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... DIC • Severe Liver ... #Coagulation #diagnosis ... #management #hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
symptoms are not caused ... heart (2-5%), liver ... (pain/abnormal ... LFT): 12-20%, spleen ... #Management #Signs
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... 50 in GCA, but normal ... vision changes, etc ... GCA #Temporal #Signs ... #Management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
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