11 results
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... unfractionated heparin ... Reduced liver synthesis ... #diagnosis #differential ... #hematology #coagulation
Appearance of Liver Lesions on Computed Tomography (CT) - Arterial Phase, Portal Venous Phase and Delayed
Appearance of Liver ... Computed Tomography (CT ... #differential #diagnosis ... #comparison #table ... #appearance #hepatology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... . heparin contamination ... thrombin inhibitors, heparin ... • Reduced liver ... #hematology #coagulation
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... Computed Tomography (CT ... #differential #diagnosis ... #comparison #table ... #appearance #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... disease, Hepatic ... presentation: Hepatic ... #Injury #Diagnosis ... #Algorithm #hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Medications - Heparin ... ) • Advanced Liver ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... DIC • Severe Liver ... INR < 2.3 - APTT ... #Coagulation #diagnosis ... treatment #management #hematology
Appearance of Liver Lesions on Contrast Enhanced Ultrasound - Early arterial, Grayscale phase, Late arterial phase,
Appearance of Liver ... #Lesions #Hepatic ... #differential #diagnosis ... #comparison #table ... #appearance #hepatology
Appearance of Liver Lesions on Magnetic Resonance Imaging (MRI) - T2, T1 precontrast, T1 portal venous,
Appearance of Liver ... #Lesions #Hepatic ... #differential #diagnosis ... #comparison #table ... #appearance #hepatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... Acquired: • Heparin ... the PT remains prolonged ... #Differential #Diagnosis ... #Hematology